Comprehensive review of neuromyelitis optica and clinical characteristics of neuromyelitis optica patients in Puerto Rico

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منابع مشابه

[Clinical overview of neuromyelitis optica].

Neuromyelitis optica (NMO) is a condition characterized by attacks of severe bilateral optic neuritis and myelitis. Historically, the prototypic syndrome was diagnosed only when these symptoms occurred nearly simultaneously as a monophasic illness. However, a contemporary view acknowledges that most commonly this condition is a relapsing disorder characterized by recurrent attacks, usually of u...

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Neuromyelitis Optica

An 11-year-old girl developed sudden visual loss in her left eye, preceding subacute myelitis by 9 months. Multifocal lesions in the central nervous system were demonstrated by magnetic resonance imaging. Although unilateral blindness is unusual, the clinical findings predominantly involving the optic nerve and spinal cord were consistent with the diagnosis of neuromyelitis optica (NMO). This c...

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Treatment of neuromyelitis optica/neuromyelitis optica spectrum disorders with methotrexate

BACKGROUND To review our experience using methotrexate as a single long-term immunosuppressant (IS) therapy in neuromyelitis optica/neuromyelitis optica spectrum disorders (NMO/NMOSD). METHODS We performed a retrospective chart review of all patients with a diagnosis of NMO/NMOSD, supported by a positive NMO-IgG testing, who were treated with methotrexate. A paired sample 2 tailed t test was ...

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Neuromyelitis Optica in Children: A Rare Entity

     Neuromyelitis optica (also known as Devic's disease or Devic's syndrome) is an uncommon disorder in pediatric age group, and is characterized by acute or subacute optic neuritis and transverse myelitis. Here we report an 11- year- old female child with relapsing Neuromyelitis optica (NMO) confirmed by positive NMO- IgG antibody and had clinical recovery with high dose methyl prednisolone t...

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Immunotherapy of Neuromyelitis Optica

Neuromyelitis optica (NMO) is a chronic inflammatory disease of the central nervous system that affects the optic nerves and spinal cord resulting in visual impairment and myelopathy. There is a growing body of evidence that immunotherapeutic agents targeting T and B cell functions, as well as active elimination of proinflammatory molecules from the peripheral blood circulation, can attenuate d...

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ژورنال

عنوان ژورنال: Surgical Neurology International

سال: 2018

ISSN: 2152-7806

DOI: 10.4103/sni.sni_224_18